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Altered white matter microarchitecture in Parkinson’s disease: a voxel-based meta-analysis of diffusion tensor imaging studies

Xueling Suo, Du Lei, Wenbin Li, Lei Li, Jing Dai, Song Wang, Nannan Li, Lan Cheng, Rong Peng, Graham J Kemp, Qiyong Gong

《医学前沿(英文)》 2021年 第15卷 第1期   页码 125-138 doi: 10.1007/s11684-019-0725-5

摘要: This study aimed to define the most consistent white matter microarchitecture pattern in Parkinson’s disease (PD) reflected by fractional anisotropy (FA), addressing clinical profiles and methodology-related heterogeneity. Web-based publication databases were searched to conduct a meta-analysis of whole-brain diffusion tensor imaging studies comparing PD with healthy controls (HC) using the anisotropic effect size–signed differential mapping. A total of 808 patients with PD and 760 HC coming from 27 databases were finally included. Subgroup analyses were conducted considering heterogeneity with respect to medication status, disease stage, analysis methods, and the number of diffusion directions in acquisition. Compared with HC, patients with PD had decreased FA in the left middle cerebellar peduncle, corpus callosum (CC), left inferior fronto-occipital fasciculus, and right inferior longitudinal fasciculus. Most of the main results remained unchanged in subgroup meta-analyses of medicated patients, early stage patients, voxel-based analysis, and acquisition with <30 diffusion directions. The subgroup meta-analysis of medication-free patients showed FA decrease in the right olfactory cortex. The cerebellum and CC, associated with typical motor impairment, showed the most consistent FA decreases in PD. Medication status, analysis approaches, and the number of diffusion directions have an important impact on the findings, needing careful evaluation in future meta-analyses.

关键词: Parkinson’s disease     diffusion tensor imaging     fractional anisotropy     meta-analysis     anisotropic effect size–signed differential mapping    

Effect of anisotropic characteristics on the mechanical behavior of asphalt concrete overlay

Lingyun YOU, Zhanping YOU, Kezhen YAN

《结构与土木工程前沿(英文)》 2019年 第13卷 第1期   页码 110-122 doi: 10.1007/s11709-018-0476-4

摘要: Asphalt concrete (AC) overlays placed over old asphalt pavement have become an alternative to repairing and reinforcing pavements. The strength contributed by the AC overlay is strongly influenced by the anisotropic properties of the pavement material. This study was conducted to analyze the influence of anisotropy, modulus gradient properties, and the condition of the AC overlay and old pavement contact plane on the mechanical behaviors of AC overlays, as well as to quantify the influence of the degree of anisotropy on the mechanical behaviors of AC overlay by a sensitivity analysis (SA). The mechanical behaviors of the AC overlay were numerically obtained using the three-dimensional finite element method with the aid of ABAQUS a commercial program. Variations in the AC overlay’s modulus as a function of temperature as well as the contact state between the AC overlay and AC layer were considered. The SA is based on standardized regression coefficients method. Comparing the mechanical behavior in terms of surface deflection, stress, and strain of the anisotropy model against those corresponding to the isotropic model under static loads show that the anisotropic properties had greater effects on the mechanical behavior of the AC overlay. In addition, the maximum shear stress in the AC overlay was the most significant output parameter affected by the degree of anisotropy. Therefore, future research concerning the reinforcement and repair of pavements should consider the anisotropic properties of the pavement materials.

关键词: asphalt concrete overlay     anisotropy     temperature gradients     modulus gradients     finite element simulation     sensitivity analysis    

Effect of seismic wave propagation in massed medium on rate-dependent anisotropic damage growth in concrete

Alireza DANESHYAR, Hamid MOHAMMADNEZHAD, Mohsen GHAEMIAN

《结构与土木工程前沿(英文)》 2021年 第15卷 第2期   页码 346-363 doi: 10.1007/s11709-021-0694-z

摘要: Seismic modeling of massive structures requires special caution, as wave propagation effects significantly affect the responses. This becomes more crucial when the path-dependent behavior of the material is considered. The coexistence of these conditions renders numerical earthquake analysis of concrete dams challenging. Herein, a finite element model for a comprehensive nonlinear seismic simulation of concrete gravity dams, including realistic soil–structure interactions, is introduced. A semi-infinite medium is formulated based on the domain reduction method in conjunction with standard viscous boundaries. Accurate representation of radiation damping in a half-space medium and wave propagation effects in a massed foundation are verified using an analytical solution of vertically propagating shear waves in a viscoelastic half-space domain. A rigorous nonlinear finite element model requires a precise description of the material response. Hence, a microplane-based anisotropic damage–plastic model of concrete is formulated to reproduce irreversible deformations and tensorial degeneration of concrete in a coupled and rate-dependent manner. Finally, the Koyna concrete gravity dam is analyzed based on different assumptions of foundation, concrete response, and reservoir conditions. Comparison between responses obtained based on conventional assumptions with the results of the presented comprehensive model indicates the significance of considering radiation damping and employing a rigorous constitutive material model, which is pursued for the presented model.

关键词: soil–structure interaction     massed foundation     radiation damping     anisotropic damage    

Effect of particle size on coal char----NO reaction

Xiumin JIANG, Xiangyong HUANG, Jiaxun LIU, Chaoqun ZHANG

《能源前沿(英文)》 2011年 第5卷 第2期   页码 221-228 doi: 10.1007/s11708-011-0146-x

摘要: Surface nitrogen complex formation upon reaction of coal char with NO at 600°C was studied by X-ray photoelectron spectroscopy. Particle size had a noticeable effect on the magnitude of changes, which was observed on the surface of the coal char in the nitrogen functional group. The surface increased its -NO, pyridine-N-oxide, and -NO functional group contents with a decrease in particle size. The chemisorption processes of NO molecules on the char were simulated using the ab initio Hartree–Fock method and density functional theory. Molecular modeling was applied to determine the thermodynamics of the reactions. Mechanisms were proposed to explain the formation of the -NO, pyridine-N-oxide, and -NO functional groups at 600°C.

关键词: NO reduction     chemisorption     particle size     X-ray photoelectron spectroscopy     density functional theory (DFT)    

Effect of Cu-ZSM-5 catalysts with different CuO particle size on selective catalytic oxidation of N,N-Dimethylformamide

《环境科学与工程前沿(英文)》 2022年 第16卷 第10期 doi: 10.1007/s11783-022-1557-0

摘要:

● A series of Cu-ZSM-5 catalysts were tested for DMF selective catalytic oxidation.

关键词: N     N-Dimethylformamide     Selective catalytic oxidation     Cu-ZSM-5     CuO particle size    

Finite element analysis of stress concentrations and failure criteria in composite plates with circular holes

null

《机械工程前沿(英文)》 2014年 第9卷 第3期   页码 281-294 doi: 10.1007/s11465-014-0307-9

摘要:

In this study, the stress concentration factors (SCF) in cross-and-angle-ply laminated composite plates as well as in isotropic plates with single circular holes subjected to uniaxial loading is studied. A quadrilateral finite element of four-node with 32 degrees of freedom at each node, previously developed for the bending and mechanical buckling of laminated composite plates, is used to evaluate the stress distribution in laminated composite plates with central circular holes. Based up on the classical plate theory, the present finite element is a combination of a linear isoparametric membrane element and a high precision rectangular Hermitian element. The numerical results obtained by the present element compare favorably with those obtained by the analytic approaches published in literature. It is observed that the obtained results are very close to the reference results, which demonstrates the accuracy of the present element. Additionally, to determine the first ply failure (FPF) of laminated plate, several failure criterions are employed. Finally, to show the effect of ratio on the failure of plates, a number of figures are given for different fiber orientation angles.

关键词: laminated composite plates     stress concentration     geometric singularity     anisotropic effect    

Mapping the structure-activity relationship of

Worawan PANPIPAT, Hasene KESKIN, Zheng GUO

《化学科学与工程前沿(英文)》 2015年 第9卷 第1期   页码 105-113 doi: 10.1007/s11705-015-1502-x

摘要: The phase behavior of twelve synthesized -sitosteryl fatty acid esters with acyl moieties with different chain lengths (C2:0-C18:0) and different degrees of unsaturation (C18:1-C18:3) were investigated in pure and mixed Langmuir monolayers with phospholipids. The surface-pressure isotherms showed that short chain -sitosteryl fatty acid esters gave smaller mean molecular areas and had decreased monolayer stability and the long chain steryl esters did not produce collapsed plateaus. All the steryl esters displayed strong condensing effects, but there was a pronounced structural dependency: medium chain esters (C8 and C10) were less efficient than short and long chain esters. Atomic force microscopy imaging demonstrated that monolayers mixed with dipalmitoyl phosphatidylcholine (DPPC) displayed both DPPC-rich and steryl lipid-rich domains. However, the height and area differences between the two phases and the roughness and morphologic patterns were very dependent on the steryl lipid concentrations as well as the length, the degree of unsaturation and the molecular conformations of the acyl segments. These findings not only provide a better understanding of the interactions between phytosteryl hydrophobic derivatives and biomembranes, but also may be of general use for the design and engineering of phytosterol structural derivations for specific food and pharmaceutical applications.

关键词: β-sitosteryl fatty acid esters     dipalmitoyl phosphatidylcholine     Langmuir monolayer     condensing effect     structure-activity relationship    

Solving multi-objective optimal power flow problem considering wind-STATCOM using differential evolution

Belkacem MAHDAD, K. SRAIRI

《能源前沿(英文)》 2013年 第7卷 第1期   页码 75-89 doi: 10.1007/s11708-012-0222-x

摘要: In this paper, a simple strategy based differential evolution was proposed for solving the problem of multi-objective environmental optimal power flow considering a hybrid model (Wind-Shunt-FACTS). The DE algorithm optimized simultaneously a combined vector control based active power of wind sources and reactive power of multi STATCOM exchanged with the electrical power system to minimize fuel cost and emissions. The proposed strategy was examined and applied to the standard IEEE 30-bus with smooth cost function to solve the problem of security environmental economic dispatch considering multi distributed hybrid model based wind and STATCOM controllers. In addition, the proposed approach was validated on a large practical electrical power system 40 generating units considering valve point effect. Simulation results demonstrate that choosing the installation of multi type of FACTS devices in coordination with many distributed wind sources is a vital research area.

关键词: differential evolution     multi-objective function     optimal power flow     economic dispatch     valve point effect     environment     wind source     STATCOM    

Effect of size on biaxial flexural strength for cement-based materials by using a triangular plate method

Hakan T TURKER

《结构与土木工程前沿(英文)》 2022年 第16卷 第8期   页码 1017-1028 doi: 10.1007/s11709-022-0871-8

摘要: The effect of size on the biaxial flexural strength (BFS) of Portland cement mortar was investigated by using the recently proposed triangular plate method (TPM). An experimental program was conceived to study the size effect by keeping a constant water-cement ratio of 0.485, cement-sand ratio of 1:2.75, and using unreinforced triangular mortar plates of five different thicknesses and seven different side lengths. The BFS of the produced specimens was tested, and variations of BFS depending on specimen thickness and side length were determined. The results indicated that increases in triangular plate specimen side length and specimen thickness led to a decrease in the BFS of Portland cement mortar. The effect of specimen length increase on BFS was more significant than on the effect of the specimen thickness. The variations in specimens’ thickness indicated a deterministic Type I size effect, while the variations in specimens’ length showed an energetic-statistical Type I size effect.

关键词: testing     apparatus & methods     plain concrete     tensile properties     biaxial flexural strength     triangular plate method    

Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study

《化学科学与工程前沿(英文)》 2023年 第17卷 第12期   页码 1986-2000 doi: 10.1007/s11705-023-2337-5

摘要: Breakage of the C–N bond is a structure sensitive process, and the catalyst size significantly affects its activity. On the active metal nanoparticle scale, the role of catalyst size in C–N bond cleavage has not been clearly elucidated. So, Ru catalysts with variable nanoparticle sizes were obtained by modulating the reduction temperature, and the catalytic activity was evaluated using 1,2,3,4-tetrahydroquinoline and o-propylaniline with different C–N bond hybridization patterns as reactants. Results showed a 13 times higher reaction rate for sp3-hybridized C–N bond cleavage than sp2-hybridized C–N bond cleavage, while the reaction rate tended to increase first and then decrease as the catalyst nanoparticle size increased. Different concentrations of terrace, step, and corner sites were found in different sizes of Ru nanoparticles. The relationship between catalytic site variation and C–N bond cleavage activity was further investigated by calculating the turnover frequency values for each site. This analysis indicates that the variation of different sites on the catalyst is the intrinsic factor of the size dependence of C–N bond cleavage activity, and the step atoms are the active sites for the C–N bond cleavage. When Ru nanoparticles are smaller than 1.9 nm, they have a strong adsorption effect on the reactants, which will affect the catalytic performance of the Ru catalyst. Furthermore, these findings were also confirmed on other metallic Pd/Pt catalysts. The role of step sites in C–N bond cleavage was proposed using the density function theory calculations. The reactants have stronger adsorption energies on the step atoms, and step atoms have d-band center nearer to the Fermi level. In this case, the interaction with the reactant is stronger, which is beneficial for activating the C–N bond of the reactant.

关键词: sp3/sp2-hybridized C–N bond     noble metal nanoparticle     catalytic active site     turnover frequency     DFT    

An improved chaotic hybrid differential evolution for the short-term hydrothermal scheduling problem

Tahir Nadeem MALIK,Salman ZAFAR,Saaqib HAROON

《信息与电子工程前沿(英文)》 2015年 第16卷 第5期   页码 404-417 doi: 10.1631/FITEE.1400189

摘要: Short-term hydrothermal scheduling (STHTS) is a non-linear and complex optimization problem with a set of operational hydraulic and thermal constraints. Earlier, this problem has been addressed by several classical techniques; however, due to limitations such as non-linearity and non-convexity in cost curves, artificial intelligence tools based techniques are being used to solve the STHTS problem. In this paper an improved chaotic hybrid differential evolution (ICHDE) algorithm is proposed to find an optimal solution to this problem taking into account practical constraints. A self-adjusted parameter setting is obtained in differential evolution (DE) with the application of chaos theory, and a chaotic hybridized local search mechanism is embedded in DE to effectively prevent it from premature convergence. Furthermore, heuristic constraint handling techniques without any penalty factor setting are adopted to handle the complex hydraulic and thermal constraints. The superiority and effectiveness of the developed methodology are evaluated by its application in two illustrated hydrothermal test systems taken from the literature. The transmission line losses, prohibited discharge zones of hydel plants, and ramp rate limits of thermal plants are also taken into account. The simulation results reveal that the proposed technique is competent to produce an encouraging solution as compared with other recently established evolutionary approaches.

关键词: Valve-point effect     Prohibited discharge zones     Differential evolution     Chaotic sequences     Constraint handling    

一种流水车间批量调度的高效计算三阶段优化方法 Research Articles

Hai-yan WANG, Fu ZHAO, Hui-min GAO, John W. SUTHERLAND

《信息与电子工程前沿(英文)》 2019年 第20卷 第7期   页码 1002-1020 doi: 10.1631/FITEE.1700457

摘要: 在工件含批量生产任务情况下如何进行最佳生产调度是一个重要的生产计划问题。通常将批量工件划分为子批处理(称为分批优化)。若子批数较大,则会大大增加工件完成时间的计算复杂性。现有研究未能考虑此类计算时间问题。本文考虑可变子批、准备时间以及子批批量约束(传输子批批量受传输设备容量限制),提出一种求解n个工件、m台机器流水车间分批优化调度方法。所提方法包含3个阶段:初始批量划分、基于生产周期/总流程时间指标快速评价法的工件排序优化、分批传输方案调整。为验证3阶段优化方法的有效性,采用5个标准数据集进行测试。实验结果表明,所提方法能节省大量计算时间,尤其对大规模问题能提供更优解。

关键词: 批量流;流水车间调度;传输子批;可变批量;批量约束;差分进化    

非线性弹性薄膜表面效应的尺寸相关性研究

黄殿武,连媛,李凯

《中国工程科学》 2006年 第8卷 第4期   页码 54-59

摘要:

在Mindlin假设的前提下,考虑了几何非线性条件及表面效应的影响,建立了纳米尺度下尺寸相关的板状各向同性弹性薄膜模型;从哈密尔顿变分原理出发,导出了薄膜的控制方程,用公式明确阐述了由表面张力引起的符合经典板理论且与薄膜变形相关的残余膜力和弯矩;通过微小尺寸薄膜弯曲的算例,说明了表面效应与薄膜厚度的相关性,当薄膜厚度等于或者小于其内禀尺度时,表面效应对薄膜厚度表现出很强的敏感性。

关键词: 弹性薄膜     几何非线性     表面效应     内禀尺度     尺度相关    

Uncoupled state space solution to layered poroelastic medium with anisotropic permeability and compressible

Zhiyong AI, Wenze ZENG, Yichong CHENG, Chao WU

《结构与土木工程前沿(英文)》 2011年 第5卷 第2期   页码 171-179 doi: 10.1007/s11709-011-0103-0

摘要: This paper presents an uncoupled state space solution to three-dimensional consolidation of layered poroelastic medium with anisotropic permeability and compressible pore fluid. Starting from the basic equations of poroelastic medium, and introducing intermediate variables, the state space equation usually comprising eight coupled state vectors is uncoupled into two sets of equations of six and two state vectors in the Laplace-Fourier transform domain. Combined with the continuity conditions between adjacent layers and boundary conditions, the uncoupled state space solution of a layered poroelastic medium is obtained by using the transfer matrix method. Numerical results show that the anisotropy of permeability and the compressibility of pore fluid have remarkable influence on the consolidation behavior of poroelastic medium.

关键词: uncoupled state space solution     layered poroelastic medium     three-dimensional consolidation     anisotropic permeability     compressible pore fluid    

Effect of hierarchical ZSM-5 zeolite crystal size on diffusion and catalytic performance of n-heptane

Shuman Xu, Xiaoxiao Zhang, Dangguo Cheng, Fengqiu Chen, Xiaohong Ren

《化学科学与工程前沿(英文)》 2018年 第12卷 第4期   页码 780-789 doi: 10.1007/s11705-018-1733-8

摘要: Hierarchical ZSM-5 zeolite aggregates with different sizes of nanocrystals were synthesized using different amounts of the mesoporogen 3-aminopropyltriethoxysilane. The effect of the crystal size on the catalytic cracking of -heptane was investigated and the Thiele modulus and effectiveness factor were used to determine the reaction rate-limiting step. The crystal size affected the textual properties of the catalysts but not the acidic properties of the catalysts. The reaction rate was first order with respect to the -heptane concentration. Cracking over hierarchical zeolites with nanocrystal sizes larger than about 50 nm took place under transition-limiting conditions, whereas the reaction over hierarchical zeolites with nanocrystal sizes of 15 or 30 nm proceeded under reaction control conditions. Hierarchical ZSM-5 zeolite aggregates with smaller nanocrystals had better selectivity for light olefins which can be ascribed to the shorter diffusion path lengths and lower diffusion resistance in these catalysts. Furthermore, these catalysts had lower coking levels which can be attributed to the substantial number of mesopores which prevent the formation of coke precursors.

关键词: hierarchical ZSM-5     crystal size     catalytic cracking     Thiele modulus     effectiveness factor    

标题 作者 时间 类型 操作

Altered white matter microarchitecture in Parkinson’s disease: a voxel-based meta-analysis of diffusion tensor imaging studies

Xueling Suo, Du Lei, Wenbin Li, Lei Li, Jing Dai, Song Wang, Nannan Li, Lan Cheng, Rong Peng, Graham J Kemp, Qiyong Gong

期刊论文

Effect of anisotropic characteristics on the mechanical behavior of asphalt concrete overlay

Lingyun YOU, Zhanping YOU, Kezhen YAN

期刊论文

Effect of seismic wave propagation in massed medium on rate-dependent anisotropic damage growth in concrete

Alireza DANESHYAR, Hamid MOHAMMADNEZHAD, Mohsen GHAEMIAN

期刊论文

Effect of particle size on coal char----NO reaction

Xiumin JIANG, Xiangyong HUANG, Jiaxun LIU, Chaoqun ZHANG

期刊论文

Effect of Cu-ZSM-5 catalysts with different CuO particle size on selective catalytic oxidation of N,N-Dimethylformamide

期刊论文

Finite element analysis of stress concentrations and failure criteria in composite plates with circular holes

null

期刊论文

Mapping the structure-activity relationship of

Worawan PANPIPAT, Hasene KESKIN, Zheng GUO

期刊论文

Solving multi-objective optimal power flow problem considering wind-STATCOM using differential evolution

Belkacem MAHDAD, K. SRAIRI

期刊论文

Effect of size on biaxial flexural strength for cement-based materials by using a triangular plate method

Hakan T TURKER

期刊论文

Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study

期刊论文

An improved chaotic hybrid differential evolution for the short-term hydrothermal scheduling problem

Tahir Nadeem MALIK,Salman ZAFAR,Saaqib HAROON

期刊论文

一种流水车间批量调度的高效计算三阶段优化方法

Hai-yan WANG, Fu ZHAO, Hui-min GAO, John W. SUTHERLAND

期刊论文

非线性弹性薄膜表面效应的尺寸相关性研究

黄殿武,连媛,李凯

期刊论文

Uncoupled state space solution to layered poroelastic medium with anisotropic permeability and compressible

Zhiyong AI, Wenze ZENG, Yichong CHENG, Chao WU

期刊论文

Effect of hierarchical ZSM-5 zeolite crystal size on diffusion and catalytic performance of n-heptane

Shuman Xu, Xiaoxiao Zhang, Dangguo Cheng, Fengqiu Chen, Xiaohong Ren

期刊论文